Unusual Initial Presentation of Celiac Disease in Children: Three Case Reports

Background: The togetherness of invagination with celiac disease is an extremely rare condition especially in children. However, invagination may be the presenting symptom of celiac disease. Moreover, recurrent invaginations have been also reported in patients with celiac disease. Aim: To increase the awareness of clinicians about togetherness of these conditions. Case Presentation: Herein, we will discuss three children with diagnosis of celiac disease who presented with invagination and intestinal pseudo-obstruction. Conclusion: Children with pseudo-obstruction and invagination without an underlying etiology should be evaluated for the presence of celiac disease, especially if they have accompanying growth retardation or anemia and if they are at an unusual age for invagination. Further studies are warranted to elucidate the exact relationship of invagination with celiac disease.